Long-Term On-Chip Storage and Release of Liquid Reagents for Diagnostic Lab-on-a-Chip Applications

A new concept for long-term reagent storage for Labon-a-Chip (LoC) devices is described. Here we present a polymer multilayer stack with integrated stick packs for long-term storage of several liquid reagents, which are necessary for many diagnostic applications. Stick packs are widely used in packaging industry for storing solids and liquids for long time. The storage concept fulfills two main requirements: First, a long-term storage of reagents in stick packs without significant losses and interaction with surroundings, second, on demand releasing of liquids, which is realized by pushing a membrane against the stick pack through pneumatic pressure. This concept enables long-term on-chip storage of liquid reagents at room temperature and allows an easy implementation in different LoC devices. Keywords—Lab-on-a-Chip, long-term storage, reagent storage, stick pack.